The Thomsen-Friedenreich (TF) antigen is a key target for the development of anticancer vaccines, and this ongoing challenge remains relevant due to the poor immunogenicity of the TF antigen.To overcome this challenge, we adopted a bivalent conjugate design which introduced both the TF antigen and Twin Upholstered Headboard the Thomsen-nouveau (Tn)
SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells
Summary: Cellular senescence irreversibly arrests cell proliferation, accompanied by a multi-component senescence-associated secretory phenotype (SASP) that participates in several age-related diseases.Using stable isotope labeling with amino acids (SILACs) and cultured cells, we identify 343 SASP proteins that senescent human Colognes fibroblasts
Prediction of Skid Resistance Value of Glass Fiber-Reinforced Tiling Materials
This research focuses on the use of adaptive artificial neural network system for evaluating the skid resistance value (British Pendulum Number; BPN) of the Sea Glass Rings glass fiber-reinforced tiling materials.During the creation of the neural model, four main factors were considered: fiber, calcium carbonate content, sand blasting, and polishin
The environmental footprint of Holocene societies: a multi-temporal study of trails in the Judean Desert, Israel
The global distribution of footpaths and their inferred antiquity implies that they are widespread spatial and temporal anthropogenic landscape units.Arid environments are of special interest for investigating historically used footpaths, as older routes may preserve better due to minimal modern impact and slower pedogenic processes.Here we examine