Enhanced Immune Response Against the Thomsen-Friedenreich Tumor Antigen Using a Bivalent Entirely Carbohydrate Conjugate

The Thomsen-Friedenreich (TF) antigen is a key target for the development of anticancer vaccines, and this ongoing challenge remains relevant due to the poor immunogenicity of the TF antigen.To overcome this challenge, we adopted a bivalent conjugate design which introduced both the TF antigen and Twin Upholstered Headboard the Thomsen-nouveau (Tn)

read more



The environmental footprint of Holocene societies: a multi-temporal study of trails in the Judean Desert, Israel

The global distribution of footpaths and their inferred antiquity implies that they are widespread spatial and temporal anthropogenic landscape units.Arid environments are of special interest for investigating historically used footpaths, as older routes may preserve better due to minimal modern impact and slower pedogenic processes.Here we examine

read more